Naltrexone and Lactose Intolerance

Naltrexone and Lactose Intolerance

If you have lactose intolerance, you should be aware that lactose monohydrate is an inactive ingredient in naltrexone.

Monosaccharides are simple sugars that include glucose, fructose, and galactose. These simple sugars unite to create disaccharides, such as sucrose and lactose. Lactose is derived from the Latin word “lactis”, which means milk. It is found in other dairy products as well. Lactose is a combination of glucose and galactose. Usually, this disaccharide is separated into two monosaccharides without difficulty in the intestine by an enzyme called lactase.

However, if lactose is not broken down, it will not be absorbed in the small intestine, and it will pass into the colon. Bacteria in the colon will cause the lactose to ferment, which results in excessive gas being produced. For this reason, if there is inadequate lactase, the person will experience gastrointestinal side effects, including bloating, cramps, flatulence, nausea, or vomiting after ingesting lactose.

Most humans are lactose intolerant in adulthood. Lactose tolerance beyond the period of nursing has only evolved in the past 10,000 years, and it does not occur in any non-human species.

In addition to milk and dairy products, lactose is found in about 20% of prescription drugs, including naltrexone.

Inactive ingredients of Naltrexone

  • colloidal silicon dioxide
  • crospovidone
  • hydroxypropyl methylcellulose
  • lactose monohydrate
  • magnesium stearate
  • microcrystalline cellulose
  • polyethylene glycol
  • polysorbate 80
  • synthetic red iron oxide
  • synthetic yellow iron oxide
  • titanium dioxide
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